Treatment of hyperprolactinemia with cabergoline

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    Do not take a double dose to make up for the dose that you missed. This may increase the chance of you getting an unwanted side effect. If you are not sure what to do, speak to your doctor or pharmacist.PMID :. Bracco PL, Armentano.

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Treatment of hyperprolactinemia with cabergoline

Posted Mar 07, 2016 by Admin

Recommendation: Enable cookies on your browser. Find out more Support and Help 2016 Endocrine Society. Publications Clinical Guidelines Scientific Statements Endocrine News Journals Endocrinology Endocrine Reviews The Journal of Clinical Endocrinology Metabolism.Home Conditions Hyperprolactinemia Cabergoline Dosage Guide with Precautions - m. Print Applies to the following strength(s 0.5 mg The information at m is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Twenty-seven women treated with cabergoline became pregnant, and 25 delivered a healthy child. One patient had an intended abortion and another a miscarriage. In the patients with bromocriptine intolerance, normalization of PRL was reached in 84 of cases, whereas in the bromocriptine-resistant patients, PRL could.

After a normal serum prolactin level has been maintained for 6 months, the drug may be discontinued with monitoring of the serum prolactin level, to determine whether treatment should be restarted.Advanced Search Journals Endocrinology Endocrine Reviews The Journal of Clinical Endocrinology Metabolism. Molecular Endocrinology Hormones and Cancer Recent Progress in Hormone Research Books. Books for Purchase Translational Endocrinology Metabolism (TEAM ) Meeting Abstracts.

Author information 1Department of Endocrinology, Middelheim Ziekenhuis, Antwerpen, Belgium. Abstract Cabergoline is a new long-acting dopamine agonist that is very effective and well tolerated in patients with pathological hyperprolactinemia. The aim of this study was to examine, in a very large number of hyperprolactinemic patients.We also evaluated the effects of cabergoline in a large subgroup of patients with bromocriptine intolerance or -resistance. We retrospectively reviewed the files of 455 patients (102 males and 353 females) with pathological hyperprolactinemia treated with cabergoline in 9 Belgian centers.

Abstract Send to: See comment in PubMed Commons below. J Clin Endocrinol Metab. 1999 Jul;84(7 2518-22. Verhelst J 1, Abs R, Maiter D, van den Bruel A, Vandeweghe M, Velkeniers B, Mockel J, Lamberigts G, Petrossians P, Coremans P, Mahler C, Stevenaert A, Verlooy J.Among these patients, 41 had a microadenoma; 42, a macroadenoma; 16, idiopathic hyperprolactinemia; and 1, an empty sella. The median pretreatment serum PRL level was 124 microg/L (range, 16-26,250 microg/L). A subgroup of 292 patients had previously been treated with bromocriptine, of which 140 showed.

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Molecular Endocrinology Hormones and Cancer Books for Purchase For Authors. Advertise Copyright Permissions Reprints Institutional Subscriptions Statement of Principle. E-TOC Latest Tweets.Side effects were noted in 13 of patients, but only 3.9 discontinued therapy because of side effects. The median dose of cabergoline at the start of therapy was 1.0 mg/week but could be reduced to 0.5 mg/week once control was achieved.

Patients with idiopathic hyperprolactinemia or a microprolactinoma, on average, needed only half the dose of cabergoline as those with macroprolactinomas and have a higher chance of obtaining PRL normalization. Cabergoline also normalized PRL in the majority of patients with known bromocriptine intolerance or -resistance.Endocrine News Advertise Permissions Why have you reached this page? Your browser is not currently configured to accept cookies from this website. This means that the site will not run as smoothly/quickly as possible and could result in certain functionality not working as designed.

Dose Adjustments. The dosage may be increased by 0.25 mg twice a week up to a maximum dosage of 1 mg twice a week according to the patient's serum prolactin level.Increases in dosage should occur no more rapidly than every 4 weeks. Precautions Safety and effectiveness have not been established in pediatric patients (less than 18 years of age). Dialysis Data not available Other Comments If the patient does not respond adequately, and no additional.

Treatment with cabergoline normalized serum PRL levels in 86 of all patients: in 92 of 244 patients with idiopathic hyperprolactinemia or a microprolactinoma and in 77 of 181 macroadenomas. Pretreatment visual field abnormalities normalized in 70 of patients, and tumor shrinkage was seen in 67.Once PRL secretion was adequately controlled, the dose of cabergoline could often be significantly decreased, which further reduced costs of therapy. Comment in PMID : PubMed - indexed for MEDLINE. MeSH Terms, Substances MeSH Terms Adenoma/blood Adenoma/drug therapy.

We confirmed, in a large-scale retrospective study, the high efficacy and tolerability of cabergoline in the treatment of pathological hyperprolactinemia, leaving few patients with unacceptable side effects or inadequate clinical response.Patients with a macroprolactinoma needed a higher median cabergoline dose, compared with those with idiopathic hyperprolactinemia or a microprolactinoma: 1.0 mg/week vs. 0.5 mg/week, although a large overlap existed between these groups.

1999;84:251822. PubMed 3. Corsello SM, Ubertini G, Altomare M, Lovicu RM, Migneco MG, Rota CA, et al. Giant prolactinomas in men: efficacy of cabergoline treatment. Clin Endocrinol (Oxf) 2003;58:66270. PubMed 4.Add to Cabinet Add Adderall to my medicine cabinet. I am Currently Taking Researching Previously Taken Reason for taking Attention Deficit Disorder with Hyperactivity Recurring Sleep Episodes During the Day Other Did you know?